Therefore, although O antigen may serve a role in swarming by promoting wettability, the loss of O antigen blocks a regulatory pathway that links surface contact with the upregulation of flhDC expression.”
“Many intracellular pathogens remodel the actin of their host cells, and the human malaria parasite Plasmodium falciparum is no exception to this rule. The surprising finding is that several hemoglobinopathies that protect

carriers from severe malaria may do so by interfering with host actin reorganization. Here we discuss our current understanding of actin remodeling in P. falciparum-infected erythrocytes, how hemoglobinopathies interfere with this selleck screening library process, and how impaired host actin remodeling affects the virulence of P. falciparum.”
“We employed a cross-linked enzyme aggregate (CLEA) method to immobilize formate dehydrogenase (FDH) from Candida boidinii. The optimal conditions for the preparation of CLEAs were determined by examining effects of various parameters: the nature and amount of cross-linking reagent, additive concentration, cross-linking time, and pH during CLEA preparation. The recovered activities of CLEAs were significantly dependent on the concentration of Fer-1 glutaraldehyde; however, the recovered activity was not severely influenced by the content of dextran polyaldehyde as a mild cross-linker. Bovine serum

albumin (BSA) was also used as a proteic feeder and enhanced the activity recovery by 130%. The highest recovered activity of CLEA was 18% for formate oxidation reaction and

25% check details for CO2 reduction reaction. The residual activity of CLEA prepared with dextran polyaldehyde (Dex-CLEA) was over 95% after 10 cycles of reuse. The thermal stability of Dex-CLEA was increased by a factor of 3.6 more than that of the free enzyme. CLEAs of FDH could be utilized efficiently for both NADH regeneration and CO2 reduction. (C) 2013 Elsevier B.V. All rights reserved.”
“Here we present a rare case of primary mucinous adenocarcinoma of vagina treated successfully with wide local excision and post-operative radiotherapy. There was no recurrence even after four years.”
“We fabricated exchange coupled composite (ECC) L1(0) ordered, (001) oriented FePt (5nm)/Fe (5 nm) bit patterned media over a large area by diblock copolymer lithography. We formed the dot arrays of the copolymer directly on the magnetic film and used them as the etching mask. The average size of the ECC FePt/Fe pillars was about 32 nm, with a center to center distance of about 35 nm and a size distribution of about 8%. The perpendicular coercivity (H-c) of the ECC FePt/Fe patterned structures was about 4.3 kOe. Both the coercivity and the saturation field of the ECC FePt/Fe patterned structure were reduced by about 50% due to the exchange coupling between FePt and Fe in the FePt/Fe patterned structure compared to the FePt patterned structure with similar dot size and distribution.