Results: Compared with control, in the drug-naÏve group the frequency of dysfunction was significantly higher for urinary urgency (20.9% of the women, 25.9% of the men, P < 0.01), urinary incontinence (9.1%, women), retardation in initiating urination (13.1%, men); constipation (23.8%, 14.8%), diarrhea (20.3%, 21.8%); decrease in libido (42%, men), sexual intercourse (70.7%, 78.7%) orgasm
(63.6%, 65.0%), erection (92.7% of the men); and quality of life indices. No difference was found in the frequency of all three items between the drug-naÏve group and the medicated group. Conclusion: The results of the present study suggest Proteases inhibitor that major depression is a risk for all bladder, bowel and sexual dysfunction, and it significantly worsens quality of life in
patients. This finding presumably reflects that pelvic organ function is under emotional control. Amelioration of bladder, bowel, and sexual dysfunction is therefore an important target to treat patients with major depression. “
“Objectives: The present study was undertaken to investigate the association between the severity of atherosclerosis and lower urinary tract function in male patients with lower urinary tract symptoms. Methods: Male patients EPZ-6438 order with lower urinary tract symptoms were examined with routine investigation. The severity of atherosclerosis was assessed by ultrasound examination of Y-27632 2HCl carotid artery. Patients were divided into two groups: control group and atherosclerosis group. The voiding function and storage function were compared between the two groups. Results: A total of 50 men (69.9 ± 9.1 years [mean ± standard deviation]) entered the study. There was
no significant difference in age distribution (control group: 68.7 ± 7.6 years; atherosclerosis group: 72.5 ± 9.7 years) and prostate volume (control group: 26.5 ± 17.3 mL; atherosclerosis group: 22.2 ± 11.0 mL) between the two groups. In the voiding parameters, maximum flow rate in the atherosclerosis group (13.4 ± 5.5 mL/s, P < 0.05) was significantly lower than that in the control group (16.7 ± 7.7 mL/s). Postvoid residual urine volume showed no significant difference between the two groups. In the storage parameters, voided volume was significantly reduced in the atherosclerosis group (161.8 ± 46 mL, P < 0.05), as compared to control group (201.1 ± 78 mL). Moreover, daytime frequency was 7.13 ± 3.02 times in the control group, and significantly higher in the atherosclerosis group (8.75 ± 2.50 times, P < 0.05). Conclusion: Development of atherosclerosis impairs both voiding and storage function independently of age, suggesting atherosclerosis leads to lower urinary dysfunction.