No severe complications occurred during
the 36-month follow-up period. Cosmetic results were remarkable. The success rate was 98.5%.
CONCLUSIONS
Phenol cauterization is an excellent surgical method for the treatment of ingrowing toenails, being simple and associated with low morbidity and a high success rate, even over the long term (36 months).
The authors have indicated no significant interest with commercial supporters.”
“Purpose of review
We reviewed AZD0156 cell line the most recent literature on solid-organ transplant (SOT) recipients regarding the clinical significance of influenza and the immunogenicity and safety of influenza vaccine in this population.
Recent findings
In SOT recipients, influenza is associated with significant graft dysfunction and even mortality. Early initiation of
antiviral therapy is associated with a reduced risk for influenza-associated complications, mainly pneumonia. The main preventive strategy against influenza in SOT recipients remains the administration of yearly influenza vaccine. Although most studies have shown that influenza vaccination is safe after transplantation, impaired responses are expected in more immunosuppressed patients. A lower immunogenicity of influenza vaccine has been described in patients receiving mycophenolate and mammalian target of rapamycin inhibitors. The optimal timing of vaccination after transplant remains to be determined, although vaccination during the early Torin 2 mouse posttransplant period appears to be safe. Novel vaccination strategies, such as intradermal vaccination or use of adjuvanted vaccines, have been evaluated
in SOT recipients, with inconclusive results to date.
Summary
The administration of influenza vaccination is strongly recommended in SOT recipients and their relatives. Further research is needed for improving the immunogenicity of influenza vaccine in this population.”
“BACKGROUND
Ingrown toenails have a tendency for recurrence. Operative interventions can be successful, and several procedures are in use.
OBJECTIVE
Retrospective evaluation, to reveal differences in postoperative pain, time to recovery, P005091 inhibitor and satisfaction with the cosmetic outcome in patients treated with a phenol (PCM) or surgical matricectomy (SM).
MATERIALS & METHODS
All matricectomy patients at the Dermatology Department of the Ludwigshafen City Hospital between 2004 and 2008 were interviewed over the telephone. Of 72 evaluable patients with a total of 112 ingrown nail sides, 33 were treated with PCM and 39 with SM. The patient group consisted of 40.3% women, the median age was 31.
RESULTS
Patients after PCM indicated two points less postoperative pain on an analogue scale from 0 to 10 (p <.001). In the PCM group, more patients recovered from the operation in less than 1 week (p=.007). Patient evaluation of cosmetic outcome was not different between the groups (p=.76), but recurrence rates were significantly higher in the PCM group (31.5%, vs 6.9% in the SM group, p=.